Toll-like Receptors in Inflammation

Toll-like receptors (TLRs) are critical mediators of the innate immune response in mammals. This family of receptors recognizes a variety of microbial products or motifs and initiates the host response to infection. Examples include TLR4 which recognizes lipopolysaccharide (LPS) from Gram-negative b...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: O'Neill, Luke A.J (Editor ), Brint, Elizabeth (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Basel : Birkhäuser Basel : Imprint: Birkhäuser, 2005.
Edición:1st ed. 2005.
Colección:Progress in Inflammation Research,
Temas:
Immunology.
Diseases.
Medical microbiology.
Cytology.
Pharmacology.
Medical Microbiology.
Cell Biology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • TLRs as bacterial sensors
  • Toll-like receptors and rheumatoid arthritis: is there a connection?
  • Toll-like receptor 9 and systemic autoimmune diseases
  • Toll-like receptors and airway disease
  • Toll-like receptors and vascular disease
  • Toll-like receptors and inflammatory bowel disease
  • Toll-like receptor signaling in the liver
  • Toll-like receptors as key sensors of viral infection
  • IRAK-4: A key kinase involved in toll-like receptor signaling and resistance to bacterial infection
  • Endogenous regulation of toll-like receptor signalling
  • Tuning of inflammatory cytokines and toll-like receptors by TIR8/SIGIRR, a member of the IL-1 receptor family with unique structure and regulation
  • Toll-like receptors as pharmacological targets.

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