Sodium Channels, Pain, and Analgesia

Sodium channels confer excitability on neurons in nociceptive pathways and exhibit neuronal tissue specific and injury regulated expression. This volume provides recent insights into the control of expression, functioning and membrane trafficking of nervous system sodium channels and reviews why sod...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Coward, Kevin (Editor ), Baker, Mark D. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Basel : Birkhäuser Basel : Imprint: Birkhäuser, 2005.
Edición:1st ed. 2005.
Colección:Progress in Inflammation Research,
Temas:
Pain medicine.
Neurosciences.
Pharmacology.
Cytology.
Pain Medicine.
Neuroscience.
Cell Biology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Voltage-gated sodium channels and pain associated with nerve injury and neuropathies
  • Current approaches for the discovery of novel NaV channel inhibitors for the treatment of brain disorders
  • Voltage-gated sodium channels and visceral pain
  • The functional interaction of accessory proteins and voltage-gated sodium channels
  • Sodium channels and nociceptive nerve endings
  • Signalling cascades that modulate the activity of sodium channels in sensory neurons
  • NaV1.8 as a drug target for pain
  • Role of voltage-gated sodium channels in oral and craniofacial pain
  • Sodium channel gating and drug blockade
  • Future directions in sodium channel research.

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