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Regulatory T Cells in Inflammation

Regulatory T-cells are essential components of the immune system, and several different subsets of regulatory T-cells have been described. Considerable regulatory function has been attributed to the CD4+CD25+ T-cell subset. These cells act by suppressing adaptive and possibly innate immune responses...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Taams, Leonie S. (Editor ), Akbar, Arne N. (Editor ), Wauben, Marca H.M (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Basel : Birkhäuser Basel : Imprint: Birkhäuser, 2005.
Edición:1st ed. 2005.
Colección:Progress in Inflammation Research,
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Origin, function and distribution of regulatory T cells
  • History of CD25+CD4+ regulatory T cells
  • "Natural" and "induced" regulatory T cells - purpose and problems associated with an emerging distinction
  • The role of interleukin-10 in regulatory-T-cell suppression: reconciling the discrepancies
  • Activation and distribution of regulatory T cells in naïve and antigen-stimulated immune systems
  • Regulatory T cells and the innate immune system
  • The potential use of regulatory T cells in immunotherapy
  • Exploiting the potential of regulatory T cells in the control of type 1 diabetes
  • Regulatory T cells in type 1 autoimmune diabetes
  • The potential for targeting CD4+CD25+ regulatory T cells in the treatment of multiple sclerosis in humans
  • Immunotherapy of rheumatoid arthritis using CD4+CD25+ regulatory T cells
  • Potential for manipulation of regulatory T cells in treatment or prevention of allergic disease
  • The role of regulatory T cells in cutaneous disorders
  • The potential role of CD25+CD4+ regulatory T cells in the induction and maintenance of transplantation tolerance in humans.