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Multiple System Atrophy

This textbook provides a comprehensive monography on multiple system atrophy (MSA), a rare and fatal neurodegenerative disorder that presents with autonomic failure and either parkinsonism (MSA-P) or cerebellar ataxia (MSA-C).The underlying neuropathology of MSA is characterized by striatonigral deg...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Wenning, Gregor K. (Editor ), Fanciulli, Alessandra (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Vienna : Springer Vienna : Imprint: Springer, 2014.
Edición:1st ed. 2014.
Temas:
Acceso en línea:Texto Completo

MARC

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245 1 0 |a Multiple System Atrophy  |h [electronic resource] /  |c edited by Gregor K. Wenning, Alessandra Fanciulli. 
250 |a 1st ed. 2014. 
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300 |a XVI, 198 p. 33 illus., 20 illus. in color.  |b online resource. 
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505 0 |a 1. Historical Review -- 2. Epidemiology -- 3. Neuropathology -- 4. Etiopathogenesis -- 5. Animal Models -- 6. Clinical Presentation -- 7. Clinical diagnostic Criteria -- 8. Natural History -- 9. Investigations -- 10. Tratment. 
520 |a This textbook provides a comprehensive monography on multiple system atrophy (MSA), a rare and fatal neurodegenerative disorder that presents with autonomic failure and either parkinsonism (MSA-P) or cerebellar ataxia (MSA-C).The underlying neuropathology of MSA is characterized by striatonigral degeneration (SND), olivopontocerebellar atrophy (OPCA) and unique oligodendroglial cytoplasmic alpha-synuclein inclusions. MSA is therefore classified among the alpha-synucleinopathies such as Parkinson`s disease, pure autonomic failure and dementia with Lewy bodies. Over the last decade there have been important advances in early diagnosis, pathogenesis research and clinical trial activity. The monography will cover the entire spectrum ranging from molecular and genetic work to symptomatic and interventional therapies. The book is written for movement disorder clinicians and basic neuroscientists interested in degenerative movement disorders. 
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700 1 |a Fanciulli, Alessandra.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
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