Gene Vaccines

The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion en...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Thalhamer, Josef (Editor ), Weiss, Richard (Editor ), Scheiblhofer, Sandra (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Vienna : Springer Vienna : Imprint: Springer, 2012.
Edición:1st ed. 2012.
Temas:
Pharmacology.
Immunology.
Clinical biochemistry.
Medical Biochemistry.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Preface
  • 1 General mechanisms of gene vaccines
  • 2 Strategies to Improve DNA Vaccine Potency: HPV-associated Cervical Cancer as a Model System
  • 3 Immune-activating mechanisms of replicase-based DNA and RNA vaccines and their role in immune-apoptosis
  • 4 Cytokine genes as molecular adjuvants for DNA vaccines
  • 5 Pharmaceutical non-viral formulations for gene vaccines
  • 6 Rational design of formulated DNA vaccines: the DermaVir approach
  • 7 In vivo electroporation
  • 8 Electroporation-based Trigrid™ delivery system (TDS) for DNA vaccine administration
  • 9 Prime Boost Regimens for Enhancing Immunity: Magnitude, Quality of Mucosal and Systemic Gene Vaccines
  • 10 Intranodal genetic immunization
  • 11 Immunotherapy of cancer with RNA vaccines
  • 12 DNA and RNA vaccines for prophylactic and therapeutic treatment of type I allergy
  • 13 Approved veterinary vaccines - paving the way to products for human use
  • 14 Current status of regulations for DNA vaccines
  • 15 State of the art production of antibiotic resistance-free plasmid DNA
  • 16 Industrial Manufacturing of Plasmid-DNA Products for Gene Vaccination and Therapy.  .

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