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Structural Bioinformatics of Membrane Proteins

This book is the first one specifically dedicated to the structural bioinformatics of membrane proteins. With a focus on membrane proteins from the perspective of bioinformatics, the present work covers a broad spectrum of topics in evolution, structure, function, and bioinformatics of membrane prot...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Frishman, D. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Vienna : Springer Vienna : Imprint: Springer, 2010.
Edición:1st ed. 2010.
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Evolutionary origins of membrane proteins
  • Molecular archeological studies of transmembrane transport systems
  • Resource for structure related information on transmembrane proteins
  • Topology prediction of membrane proteins: how distantly related homologs come into play
  • Transmembrane beta-barrel protein structure prediction
  • Multiple alignment of transmembrane protein sequences
  • Prediction of re-entrant regions and other structural features beyond traditional topology models
  • Dual-topology: one sequence, two topologies
  • Predicting the burial/exposure status of transmembrane residues in helical membrane proteins
  • Helix-helix interaction patterns in membrane proteins
  • Predicting residue and helix contacts in membrane proteins
  • Natural constraints, folding, motion, and structural stability in transmembrane helical proteins
  • Prediction of three-dimensional transmembrane helical protein structures
  • GPCRs: Past, present, and future.