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MicroRNAs in malignant tumors of the skin First steps of tiny players in the skin to a new world of genomic medicine /

Michael Sand gives the reader an overview of current techniques in expression profiling of miRNAs and their maturation machinery in the skin. This book is a postdoctoral thesis on miRNAs in cutaneous malignant melanoma and non-melanoma skin cancer with a focus on the miRNA processing machinery and m...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Sand, Michael (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Wiesbaden : Springer Fachmedien Wiesbaden : Imprint: Springer, 2016.
Edición:1st ed. 2016.
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Introduction
  • Objectives of this work
  • Summary and discussion of this work
  • Closing remarks
  • Paper 1: Expression levels of the microRNA processing enzymes Drosha and Dicer in epithelial skin cancer
  • Paper 2: Expression levels of the microRNA maturing microprocessor complex component DGCR8 and the RNA- induced silencing complex (RISC) components argonaute-1, argonaute-2, PACT, TARBP1 and TARBP2 in epithelial skin cancer
  • Paper 3: Expression of microRNAs in basal cell carcinoma
  • Paper 4: Microarray analysis of microRNA expression in cutaneous squamous cell carcinoma
  • Paper 5: The miRNA machinery in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases and benign melanocytic nevi
  • Paper 6: Immunohistochemical expression patterns of the microRNA-processing enzyme Dicer in cutaneous malignant melanomas, benign melanocytic nevi and dysplastic melanocytic nevi
  • Paper 7: Comparative microarray analysis of microRNA expression profiles in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases and benign melanocytic nevi
  • Paper 8: MicroRNAs and the skin: tiny players in the body's largest organ
  • Paper 9: microRNA in non-melanoma skin cancer.