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Real-Time Monitoring of Cancer Cell Metabolism for Drug Testing

Hamed Alborzinia uses the biosensor chip to monitor the metabolic and morphological changes in cancer cell lines in real time, particularly: (i) real-time measurements of basic cancer cell metabolism of different cancer cell lines; (ii) a detailed timeline of the metabolic response to cisplatin trea...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Alborzinia, Hamed (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Wiesbaden : Springer Fachmedien Wiesbaden : Imprint: Springer Spektrum, 2015.
Edición:1st ed. 2015.
Temas:
Acceso en línea:Texto Completo

MARC

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100 1 |a Alborzinia, Hamed.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
245 1 0 |a Real-Time Monitoring of Cancer Cell Metabolism for Drug Testing  |h [electronic resource] /  |c by Hamed Alborzinia. 
250 |a 1st ed. 2015. 
264 1 |a Wiesbaden :  |b Springer Fachmedien Wiesbaden :  |b Imprint: Springer Spektrum,  |c 2015. 
300 |a XIII, 153 p. 32 illus.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
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505 0 |a Drug Screening with New Perspectives -- Real-Time Monitoring of Living Cells by a Novel Online Biosensor Chip -- Anticancer Agents - Effects Measured in Real Time -- Metabolism of Cancer Cells. 
520 |a Hamed Alborzinia uses the biosensor chip to monitor the metabolic and morphological changes in cancer cell lines in real time, particularly: (i) real-time measurements of basic cancer cell metabolism of different cancer cell lines; (ii) a detailed timeline of the metabolic response to cisplatin treatment and clear detection of the time span between start of cisplatin treatment and onset of cell death, which reflects the time required for the underlying molecular mechanisms of cell fate decision; (iii) direct functional measurement of the biological activity of a key regulatory protein of cellular metabolism following the kinetic change in respiration upon SIRT3 overexpression; and (iv) the time-resolved impact of several organometallic compounds on cell metabolism and cell morphology, including unexpected and not yet understood highly significant and specific effects on cell-cell interaction and adhesion.  Contents Drug Screening with New Perspectives Real-Time Monitoring of Living Cells by a Novel Online Biosensor Chip Anticancer Agents - Effects Measured in Real Time Metabolism of Cancer Cells  Target Groups Researchers and students in the fields of biotechnology and pharmacy The Author Hamed Alborzinia graduated in veterinary medicine from Shiraz University (Iran) in 2005 and continued in the Ph.D. program, now as post-Doc, with Prof. Dr. Stefan Wölfl at Heidelberg University (IPMB), using bioanalytical techniques in research on cancer cell metabolism. 
650 0 |a Cancer. 
650 0 |a Pharmacology. 
650 0 |a Medicinal chemistry. 
650 1 4 |a Cancer Biology. 
650 2 4 |a Pharmacology. 
650 2 4 |a Medicinal Chemistry. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer Nature eBook 
776 0 8 |i Printed edition:  |z 9783658101626 
776 0 8 |i Printed edition:  |z 9783658101602 
856 4 0 |u https://doi.uam.elogim.com/10.1007/978-3-658-10161-9  |z Texto Completo 
912 |a ZDB-2-SBL 
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950 |a Biomedical and Life Sciences (SpringerNature-11642) 
950 |a Biomedical and Life Sciences (R0) (SpringerNature-43708)