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Arrestins - Pharmacology and Therapeutic Potential
This volume describes our current understanding of the biological role of visual and non-visual arrestins in different cells and tissues, focusing on the mechanisms of arrestin-mediated regulation of GPCRs and non-receptor signaling proteins in health and disease. The book covers wide range of arres...
| Clasificación: | Libro Electrónico |
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| Autor Corporativo: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2014.
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| Edición: | 1st ed. 2014. |
| Colección: | Handbook of Experimental Pharmacology,
219 |
| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- Therapeutic Potential of Small Molecules and Engineered Proteins.-Arrestin Interactions with G Protein-coupled Receptors
- Arrestin-biased GPCR Agonists
- Arrestin-1 Expression Levels, Rod Function and Health
- Protective Functions of Arrestin-1 in Photoreceptors
- Arrestin-4 and Cone Function
- Enhanced Phosphorylation-independent Arrestins and Gene Therapy
- Targeting Particular Receptors with Redesigned Non-visual Arrestins.- Arrestins binding to clathrin, AP2 and Role in GPCR trafficking
- Arrestins in Ubiquitination and Deubiquitination
- Arrestin Self-association
- Arrestin-dependent Activation of ERK and Src
- Arrestin-dependent Activation of JNK Family Kinases
- Arrestin-Mediated P38 Activation.- Arrestin-dependent PDE Localization
- Arrestins in Cell Migration
- Arrestins in Host-pathogen Interactions
- Arrestin Regulation of Small GTPases
- GPCRs and Arrestins in Airways: Implications for Asthma
- Arrestins as Regulatory Signaling Hubs in Cancer Pathways
- Arrestins in Pain and Anesthesia.