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Arrestins - Pharmacology and Therapeutic Potential
This volume describes our current understanding of the biological role of visual and non-visual arrestins in different cells and tissues, focusing on the mechanisms of arrestin-mediated regulation of GPCRs and non-receptor signaling proteins in health and disease. The book covers wide range of arres...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2014.
|
| Edición: | 1st ed. 2014. |
| Colección: | Handbook of Experimental Pharmacology,
219 |
| Temas: | |
| Acceso en línea: | Texto Completo |
MARC
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|---|---|---|---|
| 001 | 978-3-642-41199-1 | ||
| 003 | DE-He213 | ||
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| 008 | 131128s2014 gw | s |||| 0|eng d | ||
| 020 | |a 9783642411991 |9 978-3-642-41199-1 | ||
| 024 | 7 | |a 10.1007/978-3-642-41199-1 |2 doi | |
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| 245 | 1 | 0 | |a Arrestins - Pharmacology and Therapeutic Potential |h [electronic resource] / |c edited by Vsevolod V. Gurevich. |
| 250 | |a 1st ed. 2014. | ||
| 264 | 1 | |a Berlin, Heidelberg : |b Springer Berlin Heidelberg : |b Imprint: Springer, |c 2014. | |
| 300 | |a VIII, 447 p. 53 illus., 42 illus. in color. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 490 | 1 | |a Handbook of Experimental Pharmacology, |x 1865-0325 ; |v 219 | |
| 505 | 0 | |a Therapeutic Potential of Small Molecules and Engineered Proteins.-Arrestin Interactions with G Protein-coupled Receptors -- Arrestin-biased GPCR Agonists -- Arrestin-1 Expression Levels, Rod Function and Health -- Protective Functions of Arrestin-1 in Photoreceptors -- Arrestin-4 and Cone Function -- Enhanced Phosphorylation-independent Arrestins and Gene Therapy -- Targeting Particular Receptors with Redesigned Non-visual Arrestins.- Arrestins binding to clathrin, AP2 and Role in GPCR trafficking -- Arrestins in Ubiquitination and Deubiquitination -- Arrestin Self-association -- Arrestin-dependent Activation of ERK and Src -- Arrestin-dependent Activation of JNK Family Kinases -- Arrestin-Mediated P38 Activation.- Arrestin-dependent PDE Localization -- Arrestins in Cell Migration -- Arrestins in Host-pathogen Interactions -- Arrestin Regulation of Small GTPases -- GPCRs and Arrestins in Airways: Implications for Asthma -- Arrestins as Regulatory Signaling Hubs in Cancer Pathways -- Arrestins in Pain and Anesthesia. | |
| 520 | |a This volume describes our current understanding of the biological role of visual and non-visual arrestins in different cells and tissues, focusing on the mechanisms of arrestin-mediated regulation of GPCRs and non-receptor signaling proteins in health and disease. The book covers wide range of arrestin functions, emphasizing therapeutic potential of targeting arrestin interactions with individual partners. | ||
| 650 | 0 | |a Pharmacology. | |
| 650 | 0 | |a Biochemistry. | |
| 650 | 0 | |a Proteins. | |
| 650 | 0 | |a Medical genetics. | |
| 650 | 0 | |a Cytology. | |
| 650 | 1 | 4 | |a Pharmacology. |
| 650 | 2 | 4 | |a Biochemistry. |
| 650 | 2 | 4 | |a Proteins. |
| 650 | 2 | 4 | |a Clinical Genetics. |
| 650 | 2 | 4 | |a Cell Biology. |
| 700 | 1 | |a Gurevich, Vsevolod V. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9783642412004 |
| 776 | 0 | 8 | |i Printed edition: |z 9783642411984 |
| 776 | 0 | 8 | |i Printed edition: |z 9783662522998 |
| 830 | 0 | |a Handbook of Experimental Pharmacology, |x 1865-0325 ; |v 219 | |
| 856 | 4 | 0 | |u https://doi.uam.elogim.com/10.1007/978-3-642-41199-1 |z Texto Completo |
| 912 | |a ZDB-2-SBL | ||
| 912 | |a ZDB-2-SXB | ||
| 950 | |a Biomedical and Life Sciences (SpringerNature-11642) | ||
| 950 | |a Biomedical and Life Sciences (R0) (SpringerNature-43708) | ||