Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics

Currently, hemoglobin (Hb)-based oxygen carriers (HBOCs) are leading candidates as red blood cell substitutes. In addition, HBOCs are also potential oxygen therapeutics for treatment of patients with critical ischemic conditions due to atherosclerosis, diabetes and other conditions. This book will p...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Kim, Hae Won (Editor ), Greenburg, A. Gerson (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Temas:
Biomaterials.
Medicine-Research.
Biology-Research.
Medicinal chemistry.
Hematology.
Biomedical Research.
Medicinal Chemistry.
Acceso en línea:Texto Completo

MARC

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245 1 0 |a Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics  |h [electronic resource] /  |c edited by Hae Won Kim, A. Gerson Greenburg. 
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505 0 |a Brief historical account of HBOC development -- Physiology of respiration -- Oxygen transport to tissues -- Pathophysiology of acute anemia -- Global blood safety and need for safe blood supply -- Blood transfusion and its limitations -- Scientific basis and design of HBOCs -- HBOCs: a regulatory perspective -- Current HBOC products in development -- Clinical indications and clinical trials of HBOCs -- HBOCs and adverse events observed in clinical trials -- HBOC-mediated vasoactivity and hypertension -- HBOC and oxygen and nitrogen radical mediated toxicity -- HBOCs and clinical laboratory interference -- Animal models for HBOC studies -- New emerging Technologies for universal RBCs -- Future prospects. 
520 |a Currently, hemoglobin (Hb)-based oxygen carriers (HBOCs) are leading candidates as red blood cell substitutes. In addition, HBOCs are also potential oxygen therapeutics for treatment of patients with critical ischemic conditions due to atherosclerosis, diabetes and other conditions. This book will provide readers a comprehensive review of topics involved in the HBOC development. It focusses on current products and clinical applications as well as on emerging technologies and future prospects. 
650 0 |a Biomaterials. 
650 0 |a Medicine-Research. 
650 0 |a Biology-Research. 
650 0 |a Medicinal chemistry. 
650 0 |a Hematology. 
650 1 4 |a Biomaterials. 
650 2 4 |a Biomedical Research. 
650 2 4 |a Medicinal Chemistry. 
650 2 4 |a Hematology. 
700 1 |a Kim, Hae Won.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
700 1 |a Greenburg, A. Gerson.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
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776 0 8 |i Printed edition:  |z 9783642407185 
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950 |a Chemistry and Materials Science (SpringerNature-11644) 
950 |a Chemistry and Material Science (R0) (SpringerNature-43709) 

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