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Molecular Mechanisms in Legionella Pathogenesis
Legionnaires' disease, a potentially fatal type of pneumonia primarily affecting elderly and immuno-compromised persons, is caused by the ubiquitous environmental bacterium Legionella pneumophila. This book offers authoritative reviews of different facets of its virulence, focusing on comparati...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2014.
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| Edición: | 1st ed. 2014. |
| Colección: | Current Topics in Microbiology and Immunology,
376 |
| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- From amoeba to macrophages: exploring the molecular mechanisms of Legionella infection in both hosts
- The Legionella pneumophila two-component regulatory systems that participate in the regulation of Icm/Dot effectors
- Facets of small RNA-mediated regulation in Legionella pneumophila
- Type II secretion and Legionella virulence
- Effector translocation by the Legionella Icm/Dot type IV secretion system
- Modulation of small GTPases by Legionella
- Host lipidation: A mechanism for spatial regulation of Legionella effectors
- Phosphoinositides and the Legionella pathogen vacuole
- Legionella phospholipases implicated in virulence
- Cytotoxic glucosyltransferases of Legionella pneumophila
- Modulation of the ubiquitination machinery by Legionella
- Host signal transduction and protein kinases implicated in Legionella infection
- Mouse models of Legionnaires´ disease.