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Thymic Development and Selection of T Lymphocytes
The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in th...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2014.
|
| Edición: | 1st ed. 2014. |
| Colección: | Current Topics in Microbiology and Immunology,
373 |
| Temas: | |
| Acceso en línea: | Texto Completo |
MARC
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| 001 | 978-3-642-40252-4 | ||
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| 005 | 20220111133637.0 | ||
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| 245 | 1 | 0 | |a Thymic Development and Selection of T Lymphocytes |h [electronic resource] / |c edited by Thomas Boehm, Yousuke Takahama. |
| 250 | |a 1st ed. 2014. | ||
| 264 | 1 | |a Berlin, Heidelberg : |b Springer Berlin Heidelberg : |b Imprint: Springer, |c 2014. | |
| 300 | |a VII, 132 p. 11 illus., 9 illus. in color. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
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| 490 | 1 | |a Current Topics in Microbiology and Immunology, |x 2196-9965 ; |v 373 | |
| 505 | 0 | |a Development and Function of Cortical Thymic Epithelial Cells -- Mechanisms of Thymus Medulla Development And Function -- Self-peptides in TCR Repertoire Selection and Peripheral T Cell Function.- Central Tolerance Induction -- Trafficking to the Thymus -- The CD4/CD8 Lineages: Central Decisions and Peripheral Modifications for T Lymphocytes. | |
| 520 | |a The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity. | ||
| 650 | 0 | |a Immunology. | |
| 650 | 0 | |a Human physiology. | |
| 650 | 0 | |a Molecular genetics. | |
| 650 | 1 | 4 | |a Immunology. |
| 650 | 2 | 4 | |a Human Physiology. |
| 650 | 2 | 4 | |a Molecular Genetics. |
| 700 | 1 | |a Boehm, Thomas. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 700 | 1 | |a Takahama, Yousuke. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9783642402531 |
| 776 | 0 | 8 | |i Printed edition: |z 9783642402517 |
| 776 | 0 | 8 | |i Printed edition: |z 9783662511961 |
| 830 | 0 | |a Current Topics in Microbiology and Immunology, |x 2196-9965 ; |v 373 | |
| 856 | 4 | 0 | |u https://doi.uam.elogim.com/10.1007/978-3-642-40252-4 |z Texto Completo |
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| 950 | |a Biomedical and Life Sciences (SpringerNature-11642) | ||
| 950 | |a Biomedical and Life Sciences (R0) (SpringerNature-43708) | ||