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Disruption of Protein-Protein Interfaces In Search of New Inhibitors /

"Disruption of Protein-Protein Interfaces" reviews the latest developments and future perspectives in drug discovery at protein-protein interfaces, as well as including details of experimental and computational tools to tackle the subject, and highlighting the contribution of the Italian r...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Mangani, Stefano (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Drug discovery by targeting protein-protein interactions
  • Protein-Protein Interaction Inhibitors: case studies on small molecules and natural compounds
  • Disrupting Protein-Protein Interfaces using GRID Molecular Interaction Fields
  • NMR as a tool to target protein-protein interactions
  • Protein-protein interactions in the solid state The troubles of crystallizing of protein- protein complexes
  • Fluorescence observables and enzyme kinetics in the investigation of PPI modulation by small molecules Detection, mechanistic insight, functional consequences.