RNA and Cancer

In the last decade, it has become increasingly clear that RNA is not simply a messenger molecule directing protein synthesis. Rather, it has multiple, versatile functional roles in cells, especially in mammalian gene regulation, and thereby influences almost every aspect of cellular life. This book...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Wu, Jane Y. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Colección:Cancer Treatment and Research, 158
Temas:
Oncology.
Cancer.
Medical genetics.
Clinical biochemistry.
Cancer Biology.
Medical Genetics.
Medical Biochemistry.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Coupling between transcription and alternative splicing
  • Detection of alternatively spliced or processed RNAs in cancer using oligonucleotide microarray
  • Cancer-associated perturbations in alternative pre-messenger RNA splicing
  • Alternative splicing of tumor suppressors and oncogenes
  • MicroRNAs in cancer.-The perinucleolar compartment: RNA metabolism and cancer
  • Regulation of ARE-mRNA stability by cellular signaling: implications for human cancer
  • Alternative pre-mRNA splicing, cell death and cancer
  • Oligonucleotide therapeutics in cancer
  • Clinical perspective on chemo-resistance and the role of RNA processing.

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