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Coarse-Grained Modelling of DNA and DNA Self-Assembly
This thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of s...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Autor Corporativo: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2012.
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| Edición: | 1st ed. 2012. |
| Colección: | Springer Theses, Recognizing Outstanding Ph.D. Research,
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| Temas: | |
| Acceso en línea: | Texto Completo |
MARC
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| 001 | 978-3-642-30517-7 | ||
| 003 | DE-He213 | ||
| 005 | 20220118175300.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 120707s2012 gw | s |||| 0|eng d | ||
| 020 | |a 9783642305177 |9 978-3-642-30517-7 | ||
| 024 | 7 | |a 10.1007/978-3-642-30517-7 |2 doi | |
| 050 | 4 | |a QH505 | |
| 072 | 7 | |a PHVN |2 bicssc | |
| 072 | 7 | |a SCI009000 |2 bisacsh | |
| 072 | 7 | |a PHVN |2 thema | |
| 082 | 0 | 4 | |a 571.4 |2 23 |
| 100 | 1 | |a Ouldridge, Thomas E. |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
| 245 | 1 | 0 | |a Coarse-Grained Modelling of DNA and DNA Self-Assembly |h [electronic resource] / |c by Thomas E. Ouldridge. |
| 250 | |a 1st ed. 2012. | ||
| 264 | 1 | |a Berlin, Heidelberg : |b Springer Berlin Heidelberg : |b Imprint: Springer, |c 2012. | |
| 300 | |a XII, 176 p. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 490 | 1 | |a Springer Theses, Recognizing Outstanding Ph.D. Research, |x 2190-5061 | |
| 505 | 0 | |a A Novel DNA Model -- Methods -- Finite Size Effects -- Structural and Mechanical Properties of Model DNA -- Thermodynamic Properties of Model DNA -- Modelling DNA Tweezers -- Modelling a DNA Walker. | |
| 520 | |a This thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker - the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology. | ||
| 650 | 0 | |a Biophysics. | |
| 650 | 0 | |a Nanotechnology. | |
| 650 | 0 | |a Polymers. | |
| 650 | 0 | |a System theory. | |
| 650 | 0 | |a Soft condensed matter. | |
| 650 | 0 | |a Mathematical physics. | |
| 650 | 1 | 4 | |a Biophysics. |
| 650 | 2 | 4 | |a Nanotechnology. |
| 650 | 2 | 4 | |a Polymers. |
| 650 | 2 | 4 | |a Complex Systems. |
| 650 | 2 | 4 | |a Soft and Granular Matter. |
| 650 | 2 | 4 | |a Theoretical, Mathematical and Computational Physics. |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9783642305184 |
| 776 | 0 | 8 | |i Printed edition: |z 9783642436529 |
| 776 | 0 | 8 | |i Printed edition: |z 9783642305160 |
| 830 | 0 | |a Springer Theses, Recognizing Outstanding Ph.D. Research, |x 2190-5061 | |
| 856 | 4 | 0 | |u https://doi.uam.elogim.com/10.1007/978-3-642-30517-7 |z Texto Completo |
| 912 | |a ZDB-2-PHA | ||
| 912 | |a ZDB-2-SXP | ||
| 950 | |a Physics and Astronomy (SpringerNature-11651) | ||
| 950 | |a Physics and Astronomy (R0) (SpringerNature-43715) | ||