Drug Discovery in Africa Impacts of Genomics, Natural Products, Traditional Medicines, Insights into Medicinal Chemistry, and Technology Platforms in Pursuit of New Drugs /

Drug discovery originating in Africa has the potential to provide significantly improved treatment of endemic diseases such as malaria, tuberculosis and HIV/AIDS. This book critically reviews the current status of drug discovery research and development in Africa, for diseases that are a major threa...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Chibale, Kelly (Editor ), Davies-Coleman, Mike (Editor ), Masimirembwa, Collen (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2012.
Edición:1st ed. 2012.
Temas:
Medicinal chemistry.
Chemistry, Organic.
Pharmacy.
Clinical biochemistry.
Medicinal Chemistry.
Organic Chemistry.
Medical Biochemistry.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Overview of Current Drug Discovery Activities in Africa and Their Links to International Efforts to Combat Tropical Infectious Diseases
  • The National Cancer Institute and Natural Product Based Drug Discovery in Africa
  • Tuberculosis Drug Discovery: Target Identification and Validation
  • Targeting Conserved Pathways as a Strategy for Novel Drug Development: Disabling the Cellular Stress Response
  • Natural Product-Based Drug Discovery in Africa: The Need for Integration into Modern Drug-Discovery Paradigms
  • Searching for Drugs that Target Multiple Receptors for Anthelmintics from African Natural Products
  • Application of in silico, in vitro and in vivo ADMET/PK Platforms in Drug Discovery
  • Marine Bioprospecting in Southern Africa
  • Natural Products-Based Drug Discovery against Neglected Diseases with Special Reference to African Natural Resources
  • 'Now I heal with pride' - The Application of Screens-to-Nature (STN) Technology to Indigenous Knowledge Systems Research in Botswana: Implications for Drug Discovery
  • Innovative Approaches to Exploiting Traditional Medicines in Malaria
  • Anticancer Drug Repositioning against Tropical Diseases: The Example of Methotrexate in the Treatment of Malaria
  • Tackling the Problem of Antimalarial Resistance
  • Random and Rational Approaches to HIV Drug Discovery in Africa
  • Structure-Based Design of Domain-Selective Angiotensin-Converting Enzyme Inhibitors
  • Natural Products and Antimalarial Drugs. Will Africa Provide the Next Major Breakthrough?
  • Nanomedicine in the Development of Drugs for Poverty Related Diseases.

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