Ricin and Shiga Toxins Pathogenesis, Immunity, Vaccines and Therapeutics /

The intent of this volume of Current Topics in Microbiology and Immunology was to bring together a collection of in-depth and cutting edge reviews that highlight our current understanding of the biology of ricin and Shiga toxin (Stx), with the long term goal of advancing the development of counterme...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Mantis, Nicholas (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2012.
Edición:1st ed. 2012.
Colección:Current Topics in Microbiology and Immunology, 357
Temas:
Pharmacology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Preface
  • Interaction of ricin and Stx with ribosomes and the sarcin-ricin loop
  • How ricin and Stx enter and intoxicate mammalian cells
  • Cellular stress response to Stx-ricin
  • Ricin and Stx-Inflammation
  • Pathogenesis of shiga-toxin producing E.coli
  • Ricin and Stx-Interactions with the epithelium and intestinal mucosa
  • Stx Pathogenesis-Kidney complications and renal failure
  • Toxin-induced Apoptosis
  • Small Molecule Inhibitors of Ricin and STX
  • Antibody-mediated immunity to ricin
  • Stx-animal models and immunotherapies
  • Ricin- animal models and immunotherapies
  • Ricin Vaccine Development
  • Subject Index.

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