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Heteroaromatic Lipoxin A4 Analogues Synthesis and Biological Evaluation /
In this thesis Colm Duffy reviews the chemistry and biology of stable lipoxin analogues. Colm has prepared for the first time ever a pyridine-containing LXA4 analogue in enantiomerically pure form. Biological evaluation determined that both epimers at the benzylic position suppress key cytokines kno...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Autor Corporativo: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2012.
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| Edición: | 1st ed. 2012. |
| Colección: | Springer Theses, Recognizing Outstanding Ph.D. Research,
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| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- Introduction
- Recent advances in the chemistry and biology of stable synthetic Lipoxin analogues
- Synthesis of Heck coupling partner for the preparation of heteroaromatic Lipoxin A4 analogues
- Synthesis and biological evaluation of pyridine-containing Lipoxin A4 analogues
- Thiophene-containing Lipoxin A4 analogues: synthesis and their effect on the production of key cytokines
- Towards the synthesis of various heteroaromatic Lipoxin A4 analogues.