Regulatory RNAs Basics, Methods and Applications /
Recent progress in high-throughput technologies and genome wide transcriptome studies have lead to a significant scientific milestone of discovering non-coding RNAs (ncRNAs) which spans through a major portion of the genome. These RNAs most often act as riboregulators, and actively participate in th...
Clasificación: | Libro Electrónico |
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Autor Corporativo: | |
Otros Autores: | , |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2012.
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Edición: | 1st ed. 2012. |
Temas: | |
Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- Renaissance of Regulatory RNAs
- Diversity, overlap and relationships in the small RNA landscape
- Fragments of small nucleolar RNAs as a new source for non-coding RNAs
- Small regulatory RNAs (sRNAs) - key players in prokaryotic metabolism, stress response and virulence
- The canonical RNA interference pathway in animals
- Generation of functional long non-coding RNA through transcription and natural selection
- MicroRNA regulation of neuronal differentiation and plasticity
- Long Non-coding RNA Function and Expression in Cancer
- Expression profiling of ncRNAs employing RNP libraries and custom LNA/DNA microarray analysis
- Targeted methods to improve small RNA profiles generated by deep sequencing
- Biocomputational identification of bacterial small RNAs and their target binding sites
- Identifying functional miRNA targets using over-expression and knockdown methods
- Identification of lncRNAs using computational and experimental approaches
- Experimental analyses of RNA-based regulations in Bacteria
- Microregulators ruling over pluripotent stem cells.- The role of RNA-interference in targeting the cancer stem cell and clinical trials for cancer
- microRNAs in development, stem cell differentiation and regenerative medicine
- The role of microRNAs in neurodegenerative diseases: Implications for early detection and treatment
- siRNA therapeutic design: tools and challenges
- Artificial MicroRNA and its Applications
- Deep sequencing of microRNAs in cancer: Expression profiling and its applications.