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Ion Channels and Their Inhibitors

Being the crucial components of living cells, ion channels are important targets of therapeutic agents. Historically, it has been challenging to develop drugs on this target class. A major issue with target based ion channel drug development is the identification of effective small chemical leads fo...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Gupta, Satya Prakash (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2011.
Edición:1st ed. 2011.
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Structural and Functional Discrimination of Membrane
  • Proteins
  • Pharmacology of Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels
  • Advanced Molecular Modeling Techniques Applied to Ion Channels Blockers
  • Advances in Design and Development of Sodium Channel Blockers
  • Potassium Channel Blockers as Anti-arrhythmic Agents.-  hERG Potassium Channels in Drug Discovery and Development
  • Prediction of hERG Channel Inhibition Using in silico Techniques
  • Advances in Structure-Activity Relationship Studies on Potassium Channel Modulators
  • Calcium Ion Channels and Their Blockers
  • Therapeutic Potential of N-type Voltage Gated Ca2+ Channel
  • Chloride Ion Channels: Structure, Functions, and Blockers.