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NF-kB in Health and Disease

This volume is focused on a transcription factor that started its life as a B cell-specific nuclear protein, but has matured to become one of the most extensively studied transcriptional regulators, found to control many pathophysiological processes: NF-kB. Articles in the volume, all of them writte...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Karin, Michael (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2011.
Edición:1st ed. 2011.
Colección:Current Topics in Microbiology and Immunology, 349
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Preface
  • Understanding the Logic of IkappaB:NF-kappaB Regulation in Structural Terms
  • IKK regulation and human genetics
  • Specialized chromatin patterns in the control of inflammatory gene expression
  • Macrophages and NF-kappaB in Cancer
  • NF-κB/Rel proteins and the humoral immune responses of Drosophila melanogaster
  • IKK and NF-kappaB mediated functions in carcinogenesis
  • Control of NF-kappaB activity by proteolysis
  • NF-kappaB as a target for oncogenic viruses
  • NF-kappaB and Innate Immunity
  • Inhibition of NF-kappaB signaling as a strategy in disease therapy
  • NF-κB and mucosal homeostasis
  • NF-kappaB In liver cancer - the plot thickens
  • Subject index.