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Copper-Catalyzed Multi-Component Reactions Synthesis of Nitrogen-Containing Polycyclic Compounds /
A copper-catalyzed direct synthesis of 2-(aminomethyl)indoles by catalytic domino reaction including multi-component coupling was developed, and is the first example of a three-component indole formation without producing salts as a byproduct. Based on this reaction, a copper-catalyzed synthesis of...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Autor Corporativo: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2011.
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| Edición: | 1st ed. 2011. |
| Colección: | Springer Theses, Recognizing Outstanding Ph.D. Research,
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| Temas: | |
| Acceso en línea: | Texto Completo |
MARC
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| 001 | 978-3-642-15473-7 | ||
| 003 | DE-He213 | ||
| 005 | 20220116212615.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 110119s2011 gw | s |||| 0|eng d | ||
| 020 | |a 9783642154737 |9 978-3-642-15473-7 | ||
| 024 | 7 | |a 10.1007/978-3-642-15473-7 |2 doi | |
| 050 | 4 | |a QD241-441 | |
| 072 | 7 | |a PNN |2 bicssc | |
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| 072 | 7 | |a PNN |2 thema | |
| 082 | 0 | 4 | |a 547 |2 23 |
| 100 | 1 | |a Ohta, Yusuke. |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
| 245 | 1 | 0 | |a Copper-Catalyzed Multi-Component Reactions |h [electronic resource] : |b Synthesis of Nitrogen-Containing Polycyclic Compounds / |c by Yusuke Ohta. |
| 250 | |a 1st ed. 2011. | ||
| 264 | 1 | |a Berlin, Heidelberg : |b Springer Berlin Heidelberg : |b Imprint: Springer, |c 2011. | |
| 300 | |a XVI, 104 p. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 490 | 1 | |a Springer Theses, Recognizing Outstanding Ph.D. Research, |x 2190-5061 | |
| 520 | |a A copper-catalyzed direct synthesis of 2-(aminomethyl)indoles by catalytic domino reaction including multi-component coupling was developed, and is the first example of a three-component indole formation without producing salts as a byproduct. Based on this reaction, a copper-catalyzed synthesis of 3-(aminomethyl)isoquinoline was accomplished which represents an unprecedented isoquinoline synthesis through a four-component coupling reaction. Following these results, extensive application studies using one-pot palladium-, acid-, or base-promoted cyclization revealed that indole- or isoquinoline-fused polycyclic compounds can be readily synthesized through multi-component reactions. As the concept of Green Chemistry becomes ever more important, these findings may provide efficient and atom-economical approaches to the diversity-oriented synthesis of bioactive compounds containing a complex structure. This could lead to development of promising drug leads with structural complexity. The work of this thesis will go on to inspire the synthetic research of many readers. | ||
| 650 | 0 | |a Chemistry, Organic. | |
| 650 | 0 | |a Medicinal chemistry. | |
| 650 | 1 | 4 | |a Organic Chemistry. |
| 650 | 2 | 4 | |a Medicinal Chemistry. |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9783642154720 |
| 776 | 0 | 8 | |i Printed edition: |z 9783642267017 |
| 776 | 0 | 8 | |i Printed edition: |z 9783642154744 |
| 830 | 0 | |a Springer Theses, Recognizing Outstanding Ph.D. Research, |x 2190-5061 | |
| 856 | 4 | 0 | |u https://doi.uam.elogim.com/10.1007/978-3-642-15473-7 |z Texto Completo |
| 912 | |a ZDB-2-CMS | ||
| 912 | |a ZDB-2-SXC | ||
| 950 | |a Chemistry and Materials Science (SpringerNature-11644) | ||
| 950 | |a Chemistry and Material Science (R0) (SpringerNature-43709) | ||