Cargando…

Ion Channels

Ion channels play a vital role in basic physiological functions such as generation of electrical activity in nerves and muscle, control of cardiac excitability, intracellular signaling, hormone secretion, cell proliferation and many other biological processes. Because of their prevalence and the cri...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Fermini, Bernard (Editor ), Priest, Birgit (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2008.
Edición:1st ed. 2008.
Colección:Topics in Medicinal Chemistry, 3
Temas:
Acceso en línea:Texto Completo

MARC

LEADER 00000nam a22000005i 4500
001 978-3-540-79729-6
003 DE-He213
005 20220116124350.0
007 cr nn 008mamaa
008 100301s2008 gw | s |||| 0|eng d
020 |a 9783540797296  |9 978-3-540-79729-6 
024 7 |a 10.1007/978-3-540-79729-6  |2 doi 
050 4 |a RS400-431 
072 7 |a PNN  |2 bicssc 
072 7 |a PSB  |2 bicssc 
072 7 |a SCI013020  |2 bisacsh 
072 7 |a PNB  |2 thema 
082 0 4 |a 615.19  |2 23 
245 1 0 |a Ion Channels  |h [electronic resource] /  |c edited by Bernard Fermini, Birgit Priest. 
246 3 |a With contributions by numerous experts 
250 |a 1st ed. 2008. 
264 1 |a Berlin, Heidelberg :  |b Springer Berlin Heidelberg :  |b Imprint: Springer,  |c 2008. 
300 |a XIV, 171 p. 43 illus., 10 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
490 1 |a Topics in Medicinal Chemistry,  |x 1862-247X ;  |v 3 
505 0 |a Recent Advances in Ion Channel Screening Technologies -- Role of Kv7 and Cav3 Ion Channels in Pain -- Potassium Channels: Oncogenic Potential and Therapeutic Target for Cancers -- Pharmacological Rescue of Mutant CFTR Function for the Treatment of Cystic Fibrosis -- On the Process of Finding Novel and Selective Sodium Channel Blockers for the Treatment of Diseases -- Kv1.5 Potassium Channel Inhibitors for the Treatment and Prevention of Atrial Fibrillation. 
520 |a Ion channels play a vital role in basic physiological functions such as generation of electrical activity in nerves and muscle, control of cardiac excitability, intracellular signaling, hormone secretion, cell proliferation and many other biological processes. Because of their prevalence and the critical role they play in virtually all tissue types and organs, ion channels are also involved in a number of pathophysiological conditions. The aim of this volume is to review recent advances in the field of ion channel related diseases. Following an overview chapter summarizing the current state of ion channel screening technologies, five topics covering areas such as cancer, cardiac arrhythmias, cystic fibrosis, and pain have been selected, and the current state of knowledge is presented by leading experts in their field. Each chapter is structured to cover the biological rationale for the target, the current status in the development of agents to treat the disease, and future prospects and challenges facing each therapeutic area. The reader will receive a critical overview covering the progress made in the rapidly developing and complex field of ion channels and diseases. 
650 0 |a Medicinal chemistry. 
650 0 |a Pharmacology. 
650 0 |a Chemistry, Organic. 
650 0 |a Medicine-Research. 
650 0 |a Biology-Research. 
650 1 4 |a Medicinal Chemistry. 
650 2 4 |a Pharmacology. 
650 2 4 |a Organic Chemistry. 
650 2 4 |a Biomedical Research. 
700 1 |a Fermini, Bernard.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
700 1 |a Priest, Birgit.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer Nature eBook 
776 0 8 |i Printed edition:  |z 9783642098550 
776 0 8 |i Printed edition:  |z 9783540872641 
776 0 8 |i Printed edition:  |z 9783540797289 
830 0 |a Topics in Medicinal Chemistry,  |x 1862-247X ;  |v 3 
856 4 0 |u https://doi.uam.elogim.com/10.1007/978-3-540-79729-6  |z Texto Completo 
912 |a ZDB-2-CMS 
912 |a ZDB-2-SXC 
950 |a Chemistry and Materials Science (SpringerNature-11644) 
950 |a Chemistry and Material Science (R0) (SpringerNature-43709)