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Synaptic Plasticity and the Mechanism of Alzheimer's Disease

During most of the 20th century, neurodegenerative diseases remained among the most enigmatic disorders of medicine. The scientific study of these conditions was descriptive in nature, detailing the clinical and neuropathological phenotypes associated with various diseases, but etiologies and pathog...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Selkoe, Dennis J. (Editor ), Triller, Antoine (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2008.
Edición:1st ed. 2008.
Colección:Research and Perspectives in Alzheimer's Disease,
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Permanence of the Synapse and Molecular Instability
  • Cellular Biology of AMPA Receptor Trafficking and Synaptic Plasticity
  • Imaging of Experience-Dependent Structural Plasticity in the Mouse Neocortex in vivo
  • Synapse Loss, Synaptic Plasticity and the Postsynaptic Density
  • Impact of Beta Amyloid on Excitatory Synaptic Transmission and Plasticity
  • Quantitative Neuropathology in Alzheimer's Mouse Models
  • Multiple Levels of Synaptic Regulation by NMDA-type Glutamate Receptor in Normal and Disease States
  • Soluble Oligomers of the Amyloid ?-Protein: Impair Synaptic Plasticity and Behavior
  • Why Alzheimer's is a Disease of Memory: Synaptic Targeting by Pathogenic A? Oligomers (ADDLs)
  • Synaptic Transmission Dynamically Modulates Interstitial Fluid Amyloid-? Levels
  • A?-Induced Toxicity Mediated by Caspase Cleavage of the Amyloid Precursor Protein (APP)
  • Long-Term Potentiation and A?: Targeting A? Species, Cellular Mechanisms and Putative Receptors
  • Genes, Synapses and Autism Spectrum Disorders.