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Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunology

This monograph deals with the impact of classical genetics in immunology, prov- ing examples of how large immunological questions were solved, and new fields opened to analysis through the study of phenotypes, either spontaneous or induced. As broad as biology has become, there are those who do not...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Beutler, Bruce (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2008.
Edición:1st ed. 2008.
Colección:Current Topics in Microbiology and Immunology, 321
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Immunodeficiency
  • The Forward Genetic Dissection of Afferent Innate Immunity
  • Genetic Analysis of Resistance to Infections in Mice: A/J meets C57BL/6J
  • Host Defenses Against Human Papillomaviruses: Lessons from Epidermodysplasia Verruciformis
  • Innate Resistance to Flavivirus Infections and the Functions of 2?-5? Oligoadenylate Synthetases
  • Cmv1 and Natural Killer Cell Responses to Murine Cytomegalovirus Infection
  • Genetic Dissection of Host Resistance to Mycobacterium tuberculosis: The sst1 Locus and the Ipr1 Gene
  • Self-Reactivity
  • Scurfy, the Foxp3 Locus, and the Molecular Basis of Peripheral Tolerance
  • Fevers, Genes, and Innate Immunity
  • Itchy Mice: The Identification of a New Pathway for the Development of Autoimmunity
  • TIM Gene Family and Their Role in Atopic Diseases.