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RNA Interference

In the last few years the major effect that RNAi has had in invertebrate systems like C.elegans and drosophila is beginning to take hold in mammalian systems through both single gene knockdown experiments and genome-scale screens. In the next decade, there will no doubt be both notable successes and...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Paddison, Patrick J. (Editor ), Vogt, Peter K. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2008.
Edición:1st ed. 2008.
Colección:Current Topics in Microbiology and Immunology, 320
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • RNA Interference in Mammalian Cell Systems
  • RNAi Pathway in C. elegans: The Argonautes and Collaborators
  • Genetics and Biochemistry of RNAi in Drosophila
  • Role of Dicer in Posttranscriptional RNA Silencing
  • The Mechanism of RNase III Action: How Dicer Dices
  • MicroRNA Metabolism in Plants
  • Structure-Function Relationships Among RNA-Dependent RNA Polymerases
  • RNAi-Mediated Chromatin Silencing in Fission Yeast
  • A Role for RNAi in Heterochromatin Formation in Drosophila
  • RNA-Mediated Transcriptional Gene Silencing in Human Cells
  • RNA Silencing in Mammalian Oocytes and Early Embryos
  • Identifying Human MicroRNAs.