Cargando…

RNA Interference

In the last few years the major effect that RNAi has had in invertebrate systems like C.elegans and drosophila is beginning to take hold in mammalian systems through both single gene knockdown experiments and genome-scale screens. In the next decade, there will no doubt be both notable successes and...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Paddison, Patrick J. (Editor ), Vogt, Peter K. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2008.
Edición:1st ed. 2008.
Colección:Current Topics in Microbiology and Immunology, 320
Temas:
Acceso en línea:Texto Completo

MARC

LEADER 00000nam a22000005i 4500
001 978-3-540-75157-1
003 DE-He213
005 20220111133440.0
007 cr nn 008mamaa
008 100301s2008 gw | s |||| 0|eng d
020 |a 9783540751571  |9 978-3-540-75157-1 
024 7 |a 10.1007/978-3-540-75157-1  |2 doi 
050 4 |a RB155-155.8 
072 7 |a MFN  |2 bicssc 
072 7 |a MED107000  |2 bisacsh 
072 7 |a MFN  |2 thema 
082 0 4 |a 616.042  |2 23 
245 1 0 |a RNA Interference  |h [electronic resource] /  |c edited by Patrick J. Paddison, Peter K. Vogt. 
250 |a 1st ed. 2008. 
264 1 |a Berlin, Heidelberg :  |b Springer Berlin Heidelberg :  |b Imprint: Springer,  |c 2008. 
300 |a VIII, 273 p.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
490 1 |a Current Topics in Microbiology and Immunology,  |x 2196-9965 ;  |v 320 
505 0 |a RNA Interference in Mammalian Cell Systems -- RNAi Pathway in C. elegans: The Argonautes and Collaborators -- Genetics and Biochemistry of RNAi in Drosophila -- Role of Dicer in Posttranscriptional RNA Silencing -- The Mechanism of RNase III Action: How Dicer Dices -- MicroRNA Metabolism in Plants -- Structure-Function Relationships Among RNA-Dependent RNA Polymerases -- RNAi-Mediated Chromatin Silencing in Fission Yeast -- A Role for RNAi in Heterochromatin Formation in Drosophila -- RNA-Mediated Transcriptional Gene Silencing in Human Cells -- RNA Silencing in Mammalian Oocytes and Early Embryos -- Identifying Human MicroRNAs. 
520 |a In the last few years the major effect that RNAi has had in invertebrate systems like C.elegans and drosophila is beginning to take hold in mammalian systems through both single gene knockdown experiments and genome-scale screens. In the next decade, there will no doubt be both notable successes and failures as we attempt to apply this genetic tool to various biological problems for the first time in academia and industry. Through the introduction of RNAi, mammalian systems have finally gained admittance to the pantheon of model genetic systems. 
650 0 |a Medical genetics. 
650 0 |a Medical microbiology. 
650 0 |a Immunology. 
650 1 4 |a Medical Genetics. 
650 2 4 |a Medical Microbiology. 
650 2 4 |a Immunology. 
700 1 |a Paddison, Patrick J.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
700 1 |a Vogt, Peter K.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer Nature eBook 
776 0 8 |i Printed edition:  |z 9783540844112 
776 0 8 |i Printed edition:  |z 9783540751564 
776 0 8 |i Printed edition:  |z 9783642444456 
830 0 |a Current Topics in Microbiology and Immunology,  |x 2196-9965 ;  |v 320 
856 4 0 |u https://doi.uam.elogim.com/10.1007/978-3-540-75157-1  |z Texto Completo 
912 |a ZDB-2-SBL 
912 |a ZDB-2-SXB 
950 |a Biomedical and Life Sciences (SpringerNature-11642) 
950 |a Biomedical and Life Sciences (R0) (SpringerNature-43708)