Sparking Signals Kinases as Molecular Signaltransducers and Pharmacological Drug Targets in Inflammation /

Protein phosphorylation is an essential post-translational modification that modulates cell-cell communication. Substrate phosphorylation by protein kinases controls intracellular signal transduction pathways that mediate cell proliferation, migration, differentiation, and metabolism. The importance...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Baier, Gottfried (Editor ), Schraven, Burkhart (Editor ), Zügel, Ulrich (Editor ), Bonin, Arne (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2008.
Edición:1st ed. 2008.
Colección:Ernst Schering Foundation Symposium Proceedings ; 2007/3
Temas:
Pharmacology.
Immunology.
Biochemistry.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Proteomics-Based Strategies in Kinase Drug Discovery
  • PKC Isotype Functions in T Lymphocytes
  • Migration, Cell-Cell Interaction and Adhesion in the Immune System
  • Molecular Mechanisms that Control Leukocyte Extravasation Through Endothelial Cell Contacts
  • Fragment-Based Drug Discovery Using Rational Design
  • Systems Biology of T Cell Activation
  • Solving the IRAK-4 Enigma: Application of Kinase-Dead Knock-In Mice
  • Sensing, Presenting, and Regulating PAMPS
  • The Role of Diacylglycerol Kinases in T Cell Anergy.

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