Protein-Protein Interactions as New Drug Targets

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Disease-relevant intracellular protein-protein interactions occurring at defined cellular sites possess great potential as drug targets. They permit highly specific pharmacological interference with defined cellular functions. Drugs targeting such interactions are likely to act with fewer side effec...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Klussmann, Enno (Editor ), Scott, John (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2008.
Edición:1st ed. 2008.
Colección:Handbook of Experimental Pharmacology, 186
Temas:
Pharmacology.
Cytology.
Clinical biochemistry.
Medicine-Research.
Biology-Research.
Cell Biology.
Medical Biochemistry.
Biomedical Research.
Acceso en línea:Texto Completo
Descripción
Sumario:Disease-relevant intracellular protein-protein interactions occurring at defined cellular sites possess great potential as drug targets. They permit highly specific pharmacological interference with defined cellular functions. Drugs targeting such interactions are likely to act with fewer side effects than conventional medication influencing whole cell functions. This book discusses therapeutically relevant protein-protein interactions with a major focus on scaffolding proteins tethering signal transduction processes to defined cellular compartments by direct protein-protein interactions. Recent advances in the development of pharmacological agents interfering with protein-protein interactions are highlighted.
Descripción Física:XV, 512 p. online resource.
ISBN:9783540728436
ISSN:1865-0325 ;

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