Biopacemaking

The development of a bio-engineered pacemaker is of substantial clinical and also scientific interest because it promises to overcome several limitations of electronic pacemakers. Moreover it may answer the longstanding question of whether the complex structure of the sinus node is indeed a prerequi...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Spaan, J.A.E (Editor ), Coronel, Ruben (Editor ), Bakker, Jacques M. T. de (Editor ), Zaza, Antonio (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2007.
Edición:1st ed. 2007.
Colección:Series in Biomedical Engineering,
Temas:
Biomedical engineering.
Human physiology.
Application software.
Biophysics.
Cardiology.
Biomedical Engineering and Bioengineering.
Human Physiology.
Computer and Information Systems Applications.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Biopacemaking: Clinically Attractive, Scientifically a Challenge
  • Embryological Development of Pacemaker Hierarchy and Membrane Currents Related to the Function of the Adult Sinus Node: Implications for Autonomic Modulation of Biopacemakers
  • Creation of a Biological Pacemaker by Gene- or Cell-Based Approaches
  • Creating a Cardiac Pacemaker by Gene Therapy
  • Biological Pacemakers Based on If
  • Gene Therapy to Create Biological Pacemakers
  • Inhibition of Cardiomyocyte Automaticity by Electrotonic Application of Inward Rectifier Current from Kir2.1 Expressing Cells
  • Propagation of Pacemaker Activity
  • Computer Modelling of the Sinoatrial Node
  • Application of Mesenchymal Stem Cell-Derived Cardiomyocytes as Bio-pacemakers: Current Status and Problems to Be Solved
  • Enrichment of Cardiac Pacemaker-Like Cells: Neure gulin-1 and Cyclic amp Increase If-Current Density and Connexin 40 mRNA Levels in Fetal Cardiomyocytes.

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