Structural Approaches to Sequence Evolution Molecules, Networks, Populations /

Structural requirements constrain the evolution of biological entities at all levels, from macromolecules to their networks, right up to populations of biological organisms. Classical models of molecular evolution, however, are focused at the level of the symbols - the biological sequence - rather t...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Bastolla, Ugo (Editor ), Porto, Markus (Editor ), Roman, Eduardo (Editor ), Vendruscolo, Michele (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2007.
Edición:1st ed. 2007.
Colección:Biological and Medical Physics, Biomedical Engineering,
Temas:
Biophysics.
Bioinformatics.
Acceso en línea:Texto Completo

MARC

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245 1 0 |a Structural Approaches to Sequence Evolution  |h [electronic resource] :  |b Molecules, Networks, Populations /  |c edited by Ugo Bastolla, Markus Porto, Eduardo Roman, Michele Vendruscolo. 
250 |a 1st ed. 2007. 
264 1 |a Berlin, Heidelberg :  |b Springer Berlin Heidelberg :  |b Imprint: Springer,  |c 2007. 
300 |a XIX, 367 p.  |b online resource. 
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490 1 |a Biological and Medical Physics, Biomedical Engineering,  |x 2197-5647 
505 0 |a Molecules: Proteins and RNA -- Modeling Conformational Flexibility and Evolution of Structure: RNA as an Example -- Gene3D and Understanding Proteome Evolution -- The Evolution of the Globins: We Thought We Understood It -- The Structurally Constrained Neutral Model of Protein Evolution -- Towards Unifying Protein Evolution Theory -- Molecules: Genomes -- A Twenty-First Century View of Evolution: Genome System Architecture, Repetitive DNA, and Natural Genetic Engineering -- Genomic Changes in Bacteria: From Free-Living to Endosymbiotic Life -- Phylogenetic Analysis -- Molecular Phylogenetics: Mathematical Framework and Unsolved Problems -- Phylogenetics and Computational Biology of Multigene Families -- SeqinR 1.0-2: A Contributed Package to the R Project for Statistical Computing Devoted to Biological Sequences Retrieval and Analysis -- Networks -- Evolutionary Genomics of Gene Expression -- From Biophysics to Evolutionary Genetics: Statistical Aspects of Gene Regulation -- Populations -- Drift and Selection in Evolving Interacting Systems -- Adaptation in Simple and Complex Fitness Landscapes -- Genetic Variability in RNA Viruses: Consequences in Epidemiology and in the Development of New Stratgies for the Extinction of Infectivity. 
520 |a Structural requirements constrain the evolution of biological entities at all levels, from macromolecules to their networks, right up to populations of biological organisms. Classical models of molecular evolution, however, are focused at the level of the symbols - the biological sequence - rather than that of their resulting structure. Now recent advances in understanding the thermodynamics of macromolecules, the topological properties of gene networks, the organization and mutation capabilities of genomes, and the structure of populations make it possible to incorporate these key elements into a broader and deeply interdisciplinary view of molecular evolution. This book gives an account of such a new approach, through clear tutorial contributions by leading scientists specializing in the different fields involved. 
650 0 |a Biophysics. 
650 0 |a Bioinformatics. 
650 1 4 |a Biophysics. 
650 2 4 |a Bioinformatics. 
700 1 |a Bastolla, Ugo.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
700 1 |a Porto, Markus.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
700 1 |a Roman, Eduardo.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
700 1 |a Vendruscolo, Michele.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
710 2 |a SpringerLink (Online service) 
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776 0 8 |i Printed edition:  |z 9783540825579 
776 0 8 |i Printed edition:  |z 9783642071249 
776 0 8 |i Printed edition:  |z 9783540353058 
830 0 |a Biological and Medical Physics, Biomedical Engineering,  |x 2197-5647 
856 4 0 |u https://doi.uam.elogim.com/10.1007/978-3-540-35306-5  |z Texto Completo 
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912 |a ZDB-2-SXP 
950 |a Physics and Astronomy (SpringerNature-11651) 
950 |a Physics and Astronomy (R0) (SpringerNature-43715) 

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