Acute Promyelitic Leukemia Molecular Genetics, Mouse Models and Targeted Therapy /

Over the past 10 years, work on acute promyelocytic leukemia (APL) has become the paradigm of translational research that began with the discovery of a recurrent chromosomal translocation, followed by the identification of the genes and proteins involved, finding their molecular functions in transcr...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Pandolfi, Pier Paolo (Editor ), Vogt, Peter K. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2007.
Edición:1st ed. 2007.
Colección:Current Topics in Microbiology and Immunology, 313
Temas:
Cancer.
Cancer Biology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • APL as a Paradigm in Biomedical Research: A Journey Toward the Cure
  • Mouse Models of Acute Promyelocytic Leukemia
  • The PLZF Gene of t(11;17)-Associated APL
  • SUMO, the Three Rs and Cancer
  • Emerging Role for MicroRNAs in Acute Promyelocytic Leukemia
  • The Theory of APL Revisited
  • Treatment of Acute Promyelocytic Leukemia by Retinoids
  • Arsenic Trioxide and Acute Promyelocytic Leukemia: Clinical and Biological
  • Front Line Clinical Trials and Minimal Residual Disease Monitoring in Acute Promyelocytic Leukemia
  • Histone Deacetylase Inhibitors in APL and Beyond
  • Monoclonal Antibody Therapy of APL
  • Targeting APL Fusion Proteins by Peptide Interference
  • The Design of Selective and Non-selective Combination Therapy for Acute Promyelocytic Leukemia.

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