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Acute Promyelitic Leukemia Molecular Genetics, Mouse Models and Targeted Therapy /

Over the past 10 years, work on acute promyelocytic leukemia (APL) has become the paradigm of translational research that began with the discovery of a recurrent chromosomal translocation, followed by the identification of the genes and proteins involved, finding their molecular functions in transcr...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Pandolfi, Pier Paolo (Editor ), Vogt, Peter K. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2007.
Edición:1st ed. 2007.
Colección:Current Topics in Microbiology and Immunology, 313
Temas:
Acceso en línea:Texto Completo

MARC

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245 1 0 |a Acute Promyelitic Leukemia  |h [electronic resource] :  |b Molecular Genetics, Mouse Models and Targeted Therapy /  |c edited by Pier Paolo Pandolfi, Peter K. Vogt. 
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490 1 |a Current Topics in Microbiology and Immunology,  |x 2196-9965 ;  |v 313 
505 0 |a APL as a Paradigm in Biomedical Research: A Journey Toward the Cure -- Mouse Models of Acute Promyelocytic Leukemia -- The PLZF Gene of t(11;17)-Associated APL -- SUMO, the Three Rs and Cancer -- Emerging Role for MicroRNAs in Acute Promyelocytic Leukemia -- The Theory of APL Revisited -- Treatment of Acute Promyelocytic Leukemia by Retinoids -- Arsenic Trioxide and Acute Promyelocytic Leukemia: Clinical and Biological -- Front Line Clinical Trials and Minimal Residual Disease Monitoring in Acute Promyelocytic Leukemia -- Histone Deacetylase Inhibitors in APL and Beyond -- Monoclonal Antibody Therapy of APL -- Targeting APL Fusion Proteins by Peptide Interference -- The Design of Selective and Non-selective Combination Therapy for Acute Promyelocytic Leukemia. 
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