CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential

The vertebrate immune system defends the organism against invading pathogens while at the same time being self-tolerant to the body's own constituents thus preserving its integrity. Multiple mechanisms work in concert to ensure self-tolerance. Apart from purging the T cell repertoire from auto-...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Kyewski, B. (Editor ), Suri-Payer, Elisabeth (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2005.
Edición:1st ed. 2005.
Colección:Current Topics in Microbiology and Immunology, 293
Temas:
Immunology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Origin and Generation
  • Selection of CD4+CD25+ Regulatory T Cells by Self-Peptides
  • The Role of TCR Specificity in Naturally Arising CD25+ CD4+ Regulatory T Cell Biology
  • Thymic Commitment of Regulatory T Cells Is a Pathway of TCR-Dependent Selection That Isolates Repertoires Undergoing Positive or Negative Selection
  • Selection and Behavior of CD4+ CD25+ T Cells In Vivo: Lessons from T Cell Receptor Transgenic Models
  • Migration Rules: Functional Properties of Naive and Effector/Memory-Like Regulatory T Cell Subsets
  • Peripheral Generation and Function of CD4+CD25+ Regulatory T Cells
  • Dendritic Cells: Key Cells for the Induction of Regulatory T Cells?
  • Involvement of Disease Models
  • Autoimmune Gastritis Is a Well-Defined Autoimmune Disease Model for the Study of CD4+CD25+ T Cell-Mediated Suppression
  • Regulatory T Cells in Experimental Colitis
  • Autoimmune Ovarian Disease in Day 3-Thymectomized Mice: The Neonatal Time Window, Antigen Specificity of Disease Suppression, and Genetic Control
  • Regulatory T Cells in Transplantation Tolerance
  • CD4+CD25+ Regulatory T Cells in Hematopoietic Stem Cell Transplantation
  • Naturally Arising CD25+CD4+ Regulatory T Cells in Tumor Immunity
  • Phenotypic and Functional Differences Between Human CD4+CD25+ and Type 1 Regulatory T Cells.

Ejemplares similares