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Animal Models of T Cell-Mediated Skin Diseases
Pharmaceutical companies are spending increasing amounts of money on drug discovery and development. Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. T...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2005.
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| Edición: | 1st ed. 2005. |
| Colección: | Ernst Schering Foundation Symposium Proceedings ;
50 |
| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- Making Gene-Modified Mice
- High-Throughput Gene Knockouts and Phenotyping in Mice
- Modelling Gene-Environment Interactions in Th1- and Th2-Dominated Diseases of Laboratory Animals
- Animal Models of Experimental Asthma
- Models of Rheumatoid Arthritis
- Animal Models of Inflammatory Bowel Diseases
- Murine Models of Atopic Dermatitis
- Epicutaneous Sensitization with Allergens as an Atopic Dermatitis Model
- T-Cell Receptor Transgenic Models of Inflammatory Disorders: Relevance for Atopic Dermatitis?
- What Must a Model Display for Proof as a Model of Psoriasis?
- From Classical Mouse Models of Psoriasis to a Spontaneous Xenograft Model Featuring Use of AGR Mice
- The Psoriasis SCID Mouse Model: A Tool for Drug Discovery?
- Pro- and Anti-inflammatory Effects of IL-4: From Studies in Mice to Therapy of Autoimmune Diseases in Humans
- What Must a Model Display for Proof as a Model of Contact Dermatitis?
- Acute and Chronic Models of Allergic Contact Dermatitis: Advantages and Limitations
- Transgenic Mice Expressing IFN-? in the Epidermis Are a Model of Inflammatory Skin Disease and Systemic Lupus Erythematosus.