Cargando…

Coronavirus Replication and Reverse Genetics

Coronaviruses are the RNA viruses with the largest genome known to date (27 to 32 kb). Members of this virus family affect most domestic animal species, causing important socio-economical losses, and also infect humans. Human coronaviruses were known to cause the winter common cold, a mild infection...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Enjuanes, Luis (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2005.
Edición:1st ed. 2005.
Colección:Current Topics in Microbiology and Immunology, 287
Temas:
Acceso en línea:Texto Completo

MARC

LEADER 00000nam a22000005i 4500
001 978-3-540-26765-2
003 DE-He213
005 20220111132120.0
007 cr nn 008mamaa
008 100301s2005 gw | s |||| 0|eng d
020 |a 9783540267652  |9 978-3-540-26765-2 
024 7 |a 10.1007/b138038  |2 doi 
050 4 |a QR355-502 
072 7 |a PSGL  |2 bicssc 
072 7 |a MED052000  |2 bisacsh 
072 7 |a PSG  |2 thema 
082 0 4 |a 579.2  |2 23 
082 0 4 |a 616.96  |2 23 
245 1 0 |a Coronavirus Replication and Reverse Genetics  |h [electronic resource] /  |c edited by Luis Enjuanes. 
250 |a 1st ed. 2005. 
264 1 |a Berlin, Heidelberg :  |b Springer Berlin Heidelberg :  |b Imprint: Springer,  |c 2005. 
300 |a XI, 257 p. 49 illus., 18 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
490 1 |a Current Topics in Microbiology and Immunology,  |x 2196-9965 ;  |v 287 
505 0 |a Coronavirus Genome Structure and Replication -- Coronavirus Transcription: A Perspective -- The Coronavirus Replicase -- Viral and Cellular Proteins Involved in Coronavirus Replication -- Coronavirus Reverse Genetics by Targeted RNA Recombination -- Coronavirus Reverse Genetics and Development of Vectors for Gene Expression -- Reverse Genetics of Coronaviruses Using Vaccinia Virus Vectors -- Development of Mouse Hepatitis Virus and SARS-CoV Infectious cDNA Constructs. 
520 |a Coronaviruses are the RNA viruses with the largest genome known to date (27 to 32 kb). Members of this virus family affect most domestic animal species, causing important socio-economical losses, and also infect humans. Human coronaviruses were known to cause the winter common cold, a mild infection without important pathological consequences except in immuno-compromised patients. Recently, two new human coronaviruses have emerged, one causing the Severe and Acute Respiratory Syndrome (SARS) that infected more than 8000 individuals, leading to more than 800 deaths in 32 countries. This epidemic mobilized the World Health Organization, which launched travel restrictions to certain parts of the world for the first time in the last 50 years. The fact that coronaviruses, as many other viruses, crossed the species barrier to infect humans has posed a serious challenge to scientists involved in animal and human health. Control of coronavirus-induced diseases can only be the consequence of research on virus molecular biology and pathogenesis. This book contains information on virus genome structure, mechanism of replication and transcription, and the development of tools that make possible reverse genetic studies to understand virus-host interactions and the molecular basis of virus pathogenesis. The book also provides essential information for the development of classical and recombinant vaccines to control coronavirus infections. 
650 0 |a Virology. 
650 1 4 |a Virology. 
700 1 |a Enjuanes, Luis.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer Nature eBook 
776 0 8 |i Printed edition:  |z 9783642059971 
776 0 8 |i Printed edition:  |z 9783540801603 
776 0 8 |i Printed edition:  |z 9783540214946 
830 0 |a Current Topics in Microbiology and Immunology,  |x 2196-9965 ;  |v 287 
856 4 0 |u https://doi.uam.elogim.com/10.1007/b138038  |z Texto Completo 
912 |a ZDB-2-SBL 
912 |a ZDB-2-SXB 
950 |a Biomedical and Life Sciences (SpringerNature-11642) 
950 |a Biomedical and Life Sciences (R0) (SpringerNature-43708)