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Inhibitors of Protein Kinases and Protein Phosphates
The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both ba...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2005.
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| Edición: | 1st ed. 2005. |
| Colección: | Handbook of Experimental Pharmacology,
167 |
| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- Protein Kinase Inhibitors for the Treatment of Disease: The Promise and the Problems
- General Aspects of PKs Inhibition
- New Design Strategies for Ligands That Target Protein Kinase-Mediated Protein-Protein Interactions
- Pharmacological Potential and Inhibitors of Individual Classes of Protein Kinases
- The Paullones: A Family of Pharmacological Inhibitors of Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3
- Pharmacological Potential of p38 MAPK Inhibitors
- Inhibitors of PKA and Related Protein Kinases
- Inhibitors of Protein Kinase CK2: Structural Aspects
- Aminoglycoside Kinases and Antibiotic Resistance
- Pharmacological Potential and Inhibitors of Individual Classes of Protein Phosphatases
- Protein Tyrosine Phosphatases as Therapeutic Targets
- Structure-Based Design of Protein Tyrosine Phosphatase Inhibitors
- Biological Validation of the CD45 Tyrosine Phosphatase as a Pharmaceutical Target
- Serine/Threonine Protein Phosphatase Inhibitors with Antitumor Activity
- Inhibitors in Clinical Use or Advanced Clinical Trials
- Clinical Immunosuppression using the Calcineurin-Inhibitors Ciclosporin and Tacrolimus
- Targeted Therapy with Imatinib: An Exception or a Rule?
- Clinical Aspects of Imatinib Therapy
- Isoquinolinesulfonamide: A Specific Inhibitor of Rho-Kinase and the Clinical Aspect of Anti-Rho-Kinase Therapy
- Discovery and Development of Iressa: The First in a New Class of Drugs Targeted at the Epidermal Growth Factor Receptor Tyrosine Kinase.