GABAB Receptor

An up-to-date comprehensive overview of the GABA B receptor system with a particular focus on the most recent therapeutic applications and potential. This receptor system has recently been implicated in several diseases and disorders including gastroesophageal reflux disease, epilepsy, mood disorder...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Colombo, Giancarlo (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Humana, 2016.
Edición:1st ed. 2016.
Colección:The Receptors, 29
Temas:
Neurosciences.
Neurology .
Neuroscience.
Neurology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • 1. Historical Perspectives on the GABAB Receptor
  • Section 1. Chemistry
  • 2. Chemistry of GABAB Receptor Ligands: Focus on Agonists and Antagonists
  • 3. Chemistry of GABAB Receptor Ligands: Focus on Positive Allosteric Modulators
  • Section 2. Molecular Biology, Biochemistry, & Physiology
  • 4. Molecular Structure and Trafficking of the GABAB Receptor
  • 5. Distribution and Localization of the GABAB Receptor
  • 6. Activation Mechanism and Allosteric Properties of the GABAB Receptor
  • 7. Modulation of Neurotransmission by the GABAB Receptor
  • 8. GABAB Receptor Functions In The Mesolimbic Dopamine System
  • Section 3. Pharmacology
  • 9. Drug Discrimination Studies for Investigations on the Mechanisms of Action of GABAB Receptor Ligands
  • 10. Targeting the GABAB Receptor for the Treatment of Epilepsy
  • 11. Targeting the GABAB Receptor for the Treatment of Pain
  • 12. Targeting the GABAB Receptor for the Treatment of Psychiatric Disorders
  • 13. Targeting the GABAB Receptor for the Treatment of Fragile X Syndrome and Autism Spectrum Disorders
  • 14. Targeting the GABAB Receptor for the Treatment of Substance Use Disorder
  • 15. Targeting the GABAB Receptor for the Treatment of Alcohol Use Disorder
  • 16. Targeting GABAB Receptors for the Treatment of Gastroesophageal Reflux Disease and Chronic Cough
  • 17. Baclofen: Therapeutic Use and Potential of the Prototypic GABAB Receptor Agonist
  • 18. Allosteric Modulators: The New Generation of GABAB Receptor Ligands
  • 19. GABAB Receptor Antagonists as Cognition Enhancers.

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