Simple Mathematical Models of Gene Regulatory Dynamics

This is a short and self-contained introduction to the field of mathematical modeling of gene-networks in bacteria. As an entry point to the field, we focus on the analysis of simple gene-network dynamics. The notes commence with an introduction to the deterministic modeling of gene-networks, with e...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Mackey, Michael C. (Autor), Santillán, Moisés (Autor), Tyran-Kamińska, Marta (Autor), Zeron, Eduardo S. (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2016.
Edición:1st ed. 2016.
Colección:Lecture Notes on Mathematical Modelling in the Life Sciences,
Temas:
Molecular genetics.
Biomathematics.
Bioinformatics.
Mathematics.
Differential equations.
Probabilities.
Molecular Genetics.
Mathematical and Computational Biology.
Computational and Systems Biology.
Applications of Mathematics.
Differential Equations.
Probability Theory.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Introduction
  • Part I Deterministic Modeling Techniques
  • 1.Generic deterministic models of prokaryotic gene regulation
  • 2.General dynamic considerations
  • Part II Dealing with Noise
  • 3.Master equation modeling approaches
  • 4.Noise effects in gene regulation: Intrinsic versus extrinsic
  • Part III Specific Examples
  • 5.The lactose operon
  • 6.The tryptophan operon
  • 7.The Lysis-Lysogeny Switch
  • Index
  • References.

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