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Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy
This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these t...
| Clasificación: | Libro Electrónico |
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| Autor Corporativo: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cham :
Springer International Publishing : Imprint: Springer,
2016.
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| Edición: | 1st ed. 2016. |
| Colección: | Resistance to Targeted Anti-Cancer Therapeutics,
9 |
| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- Introduction
- Basic rules of T cell migration
- Regulation of anti-tumor T cell migration and function: contribution of real-time imaging
- Vascular normalization, T cell trafficking and anti-tumor immunity
- Disruption of anti-tumor T cell responses by cancer-associated fibroblasts
- Cancer-associated Tertiary Lymphoid Structures, from basic knowledge toward therapeutic target in clinic
- Homing Improvement: Boosting T Cell Trafficking for Cancer Immunotherapy
- Chemokines and T cell trafficking into tumors. Strategies to enhance recruitment of T cells into tumors
- Strategies to enhance migration and persistence of chimeric antigen receptor (CAR)-T cells into tumors.