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Systems Biology of Tumor Microenvironment Quantitative Modeling and Simulations /

This edited volume discusses the complexity of tumor microenvironments during cancer development, progression and treatment. Each chapter presents a different mathematical model designed to investigate the interactions between tumor cells and the surrounding stroma and stromal cells. The topics cove...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Rejniak, Katarzyna A. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2016.
Edición:1st ed. 2016.
Colección:Advances in Experimental Medicine and Biology, 936
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Foreword
  • Preface
  • List of Contributors
  • Image Analysis of the Tumor Microenvironment
  • Hypoxia in Gliomas: Opening Therapeutical Opportunities Using a Mathematical-Based Approach
  • Computer Simulations of the Tumor Vasculature: Applications to Interstitial Fluid Flow, Drug Delivery, and Oxygen
  • Cell-ECM Interactions in Tumor Invasion
  • Circulating Tumor Cells: When Solid tumor Meets Fluid Microenvironment
  • Modeling Proteolytically Driven Tumor Lymphangiogenesis
  • Positive feedback loops between inflammatory, bone and cancer cells during metastatic niche construction
  • Microenvironmental Niches and Sanctuaries: a Route to Acquired Resistance
  • The Tumor Microenvironment as a Barrier to Cancer Nanotherapy
  • Microenvironment-Mediated Modeling of Tumor Response to Vascular-Targeting Drugs
  • Optimizing Chemotherapeutic Anti-Cancer Treatment and the Tumor Microenvironment: An Analysis of Mathematical Models
  • Progress towards computational 3-D multicellular systems biology
  • Index.