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Efflux-Mediated Antimicrobial Resistance in Bacteria Mechanisms, Regulation and Clinical Implications /

This book, written by leading international experts, provides a comprehensive, current examination of transport-mediated antimicrobial resistance. As a particularly powerful mechanism of multidrug resistance, an in-depth examination of efflux pumps is conducted with bacteria of major public health c...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Li, Xian-Zhi (Editor ), Elkins, Christopher A. (Editor ), Zgurskaya, Helen I. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Adis, 2016.
Edición:1st ed. 2016.
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • I-Bacterial drug efflux pumps: structures and transport mechanisms
  • 1.Structures and transport mechanisms of RND efflux pumps
  • 2.Structural and molecular landscape of MFS and MATE efflux pumps
  • 3.Small multidrug resistance efflux pumps
  • 4.Structures and transport mechanisms of the ABC efflux pumps
  • 5.Multidrug efflux in the context of two-membrane cell envelopes
  • II-Bacterial drug efflux pumps in antimicrobial resistance: substrates, regulation and clinical significance
  • 6.Antimicrobial resistance in bacteria: an overview of mechanisms and role of drug efflux pumps
  • 7.Antimicrobial drug efflux pumps in Staphylococcus aureus
  • 8.Antimicrobial drug efflux pumps in other Gram-positive bacteria
  • 9.Antimicrobial drug efflux pumps in Escherichia coli
  • 10.Antimicrobial drug efflux pumps in Salmonella
  • 11.Antimicrobial drug efflux pumps in Enterobacter and Klebsiella
  • 12.Antimicrobial resistance and drug efflux pumps in Vibrio and Legionella
  • 13.Antimicrobial resistance and drug efflux pumps in Acinetobacter
  • 14.Antimicrobial drug efflux pumps in Pseudomonas aeruginosa
  • 15.Antimicrobial drug efflux pumps in Stenotrophomona maltophilia
  • 16.Antimicrobial drug efflux pumps in Burkholderia
  • 17.Efflux pumps in Neisseria gonorrhoeae: contributions to antimicrobial resistance and virulence
  • 18.Efflux pumps in Campylobacter: key players for antimicrobial resistance and environmental adaption
  • 19.Antimicrobial resistance and drug efflux pumps in Helicobacter
  • 20.Antimicrobial resistance and drug efflux pumps in Bacteroides
  • 21.Efflux pumps in mycobacteria: antimicrobial resistance, physiological functions, and role in pathogenicity
  • 22.Antimicrobial drug efflux genes and pumps in bacteria of animal and environmental origin
  • 23.Role of plasmid-encoded drug efflux pumps in antimicrobial resistance
  • 24.Influence of regulatory RNAs on antimicrobial resistance and efflux mechanisms
  • III.Role of drug efflux pumps beyond antimicrobial resistance: natural functions
  • 25.The relationship between bacterial multidrug efflux pumps and biofilm formation
  • 26.Antimicrobial drug efflux systems as components of bacterial stress responses
  • 27.Involvment of antimicrobial drug efflux systems in bacterial fitness and virulence
  • IV. Antimicrobial development and efflux pump inhibitors
  • 28.Impact of antimicrobial drug efflux pumps on antimicrobial discovery and development
  • 29.Antimicrobial drug efflux pump inhibitors
  • 30.Multidrug efflux pumps and their inhibitors characterized by computational modeling.