Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy New Perspectives and Opportunities /

This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanis...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Gregory, Christopher D. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2016.
Edición:1st ed. 2016.
Colección:Advances in Experimental Medicine and Biology, 930
Temas:
Cancer.
Cell death.
Medicine-Research.
Biology-Research.
Cancer Biology.
Cell Death.
Biomedical Research.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Foreword
  • Preface
  • 1. Molecular Cell Biology of Apoptosis and Necroptosis in Cancer
  • 2. Clearance of Dying Cells by Phagocytes: Mechanisms and Implications for Disease Pathogenesis
  • 3. Micro-environmental Effects of Cell Death in Malignant Disease
  • 4. Apoptotic Caspases in Promoting Cancer: Implications from Their Roles in Development and Tissue Homeostasis
  • 5. Axl and Mer Receptor Tyrosine Kinases: Distinct and Non-overlapping Roles in Inflammation and Cancer?
  • 6. Immunogenic Apoptotic Cell Death and Anti-cancer Immunity
  • 7. Cancer Cell Death-inducing Radiotherapy - Impact on Local Tumour Control, Tumour Cell Proliferation and Induction of Systemic Anti-tumour Immunity
  • 8. Novel Approaches to Apoptosis-inducing Therapies
  • 9. Killing Is Not Enough - How Apoptosis Hijacks Tumor-associated Macrophages to Promote Cancer Progression
  • Index.

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