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|a 9783319394060
|9 978-3-319-39406-0
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|a 10.1007/978-3-319-39406-0
|2 doi
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|a 616.994
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|a Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy
|h [electronic resource] :
|b New Perspectives and Opportunities /
|c edited by Christopher D. Gregory.
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|a 1st ed. 2016.
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|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2016.
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|a XVII, 247 p. 29 illus., 28 illus. in color.
|b online resource.
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|a text
|b txt
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|a computer
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|a online resource
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|a text file
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|a Advances in Experimental Medicine and Biology,
|x 2214-8019 ;
|v 930
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|a Foreword -- Preface -- 1. Molecular Cell Biology of Apoptosis and Necroptosis in Cancer -- 2. Clearance of Dying Cells by Phagocytes: Mechanisms and Implications for Disease Pathogenesis -- 3. Micro-environmental Effects of Cell Death in Malignant Disease -- 4. Apoptotic Caspases in Promoting Cancer: Implications from Their Roles in Development and Tissue Homeostasis -- 5. Axl and Mer Receptor Tyrosine Kinases: Distinct and Non-overlapping Roles in Inflammation and Cancer? -- 6. Immunogenic Apoptotic Cell Death and Anti-cancer Immunity -- 7. Cancer Cell Death-inducing Radiotherapy - Impact on Local Tumour Control, Tumour Cell Proliferation and Induction of Systemic Anti-tumour Immunity -- 8. Novel Approaches to Apoptosis-inducing Therapies -- 9. Killing Is Not Enough - How Apoptosis Hijacks Tumor-associated Macrophages to Promote Cancer Progression -- Index.
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|a This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic apoptotic cell death and anti-cancer immunity and cancer cell death-inducing radiotherapy. This book places the onco-biology of apoptosis in clear and objective perspective through an expertly synthesized series of reviews. Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy is a deft and thorough exploration of cutting-edge research in apoptosis and anti-cancer mechanisms from basic biology to oncology. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike.
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|a Cancer.
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|a Cell death.
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|a Medicine-Research.
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|a Biology-Research.
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|a Cancer Biology.
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|a Cell Death.
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|a Biomedical Research.
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|a Gregory, Christopher D.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
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|a SpringerLink (Online service)
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|t Springer Nature eBook
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|i Printed edition:
|z 9783319394046
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|i Printed edition:
|z 9783319394053
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|i Printed edition:
|z 9783319818801
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|a Advances in Experimental Medicine and Biology,
|x 2214-8019 ;
|v 930
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|u https://doi.uam.elogim.com/10.1007/978-3-319-39406-0
|z Texto Completo
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|a ZDB-2-SBL
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|a ZDB-2-SXB
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|a Biomedical and Life Sciences (SpringerNature-11642)
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|a Biomedical and Life Sciences (R0) (SpringerNature-43708)
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