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Translational Neuropsychopharmacology
This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fai...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cham :
Springer International Publishing : Imprint: Springer,
2016.
|
| Edición: | 1st ed. 2016. |
| Colección: | Current Topics in Behavioral Neurosciences,
28 |
| Temas: | |
| Acceso en línea: | Texto Completo |
MARC
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| 008 | 160922s2016 sz | s |||| 0|eng d | ||
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| 024 | 7 | |a 10.1007/978-3-319-33913-9 |2 doi | |
| 050 | 4 | |a RC321-580 | |
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| 245 | 1 | 0 | |a Translational Neuropsychopharmacology |h [electronic resource] / |c edited by Trevor W. Robbins, Barbara J. Sahakian. |
| 250 | |a 1st ed. 2016. | ||
| 264 | 1 | |a Cham : |b Springer International Publishing : |b Imprint: Springer, |c 2016. | |
| 300 | |a XII, 498 p. 124 illus., 92 illus. in color. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 490 | 1 | |a Current Topics in Behavioral Neurosciences, |x 1866-3389 ; |v 28 | |
| 505 | 0 | |a Translational mouse models of autism; Advancing towards pharmacological therapeutics -- Translatable and back-translatable measurement of impulsivity and compulsivity; convergent and divergent processes -- Translational models of gambling-related decision-making -- Translational research on nicotine dependence -- The need for treatment-responsive translatable biomarkers in alcoholism research -- On the road to translation for PTSD treatment: theoretical and practical considerations of the use of human models of conditioned fear for drug development -- Translational approaches targeting reconsolidation -- Translational assessment of reward and motivational deficits in psychiatric disorders -- Affective biases in humans and animals. Robinson -- Locomotor profiling from the rodents to the clinic and back again -- Animal models of sensori-motor gating in schizophrenia: Are they still relevant? -- Attention and the cholinergic system: relevance to schizophrenia -- Attentional-set-shifting across species -- Relating Translational Neuroimaging and Amperometric Endpoints: Utility for Neuropsychiatric Drug Discovery -- Cognitive translation using the rodent touchscreen test approach -- The Paired Associates Learning (PAL) Test: 30 years of CANTAB Translational Neuroscience From Laboratory to Bedside in Dementia Research -- Translational approaches to experimental medicine. | |
| 520 | |a This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importance of intermediate staging points between these extremes that depend on suitable translation of findings from animal studies to Phase 1 or Phase 2 studies utilising experimental medicine. . | ||
| 650 | 0 | |a Neurosciences. | |
| 650 | 0 | |a Psychiatry. | |
| 650 | 0 | |a Pharmacology. | |
| 650 | 1 | 4 | |a Neuroscience. |
| 650 | 2 | 4 | |a Psychiatry. |
| 650 | 2 | 4 | |a Pharmacology. |
| 700 | 1 | |a Robbins, Trevor W. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 700 | 1 | |a Sahakian, Barbara J. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9783319339115 |
| 776 | 0 | 8 | |i Printed edition: |z 9783319339122 |
| 776 | 0 | 8 | |i Printed edition: |z 9783319816302 |
| 830 | 0 | |a Current Topics in Behavioral Neurosciences, |x 1866-3389 ; |v 28 | |
| 856 | 4 | 0 | |u https://doi.uam.elogim.com/10.1007/978-3-319-33913-9 |z Texto Completo |
| 912 | |a ZDB-2-SBL | ||
| 912 | |a ZDB-2-SXB | ||
| 950 | |a Biomedical and Life Sciences (SpringerNature-11642) | ||
| 950 | |a Biomedical and Life Sciences (R0) (SpringerNature-43708) | ||