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Validation of Alternative Methods for Toxicity Testing
This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for meth...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cham :
Springer International Publishing : Imprint: Springer,
2016.
|
| Edición: | 1st ed. 2016. |
| Colección: | Advances in Experimental Medicine and Biology,
856 |
| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- Introduction
- Validation in support of internationally harmonised OECD Test Guidelines for assessing the safety of chemicals
- Regulatory acceptance of alternative methods in the development and approval of pharmaceuticals
- Validation of alternative in vitro methods to animal testing: concepts, challenges, processes and tools
- Practical aspects of designing and conducting validation studies involving multi-study trials
- Validation of computational methods
- Implementation of New Test Methods into Practical Testing
- Pathway Based Toxicology and Fit-for-Purpose Assays
- Evidence-based toxicology
- Validation of transcriptomics-based in vitro methods
- Ensuring the quality of stem cell-derived in vitro models for toxicity testing
- Validation of bioreactor and human-on-a-chip devices for chemical safety assessment
- Integrated approaches to testing and assessment
- International harmonization and cooperation in the validation of alternative methods
- Evolving the principles and practice of validation for new alternative approaches to toxicity testing. .