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Protein Targeting Compounds Prediction, Selection and Activity of Specific Inhibitors /
This book presents an overview of the most relevant protein knockdown techniques. Readers will find a description of the generation and use of recombinant human antibodies, ER intrabodies and peptides as well as a description of the working mechanism and potential of the inhibitory action of each of...
| Clasificación: | Libro Electrónico |
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| Autor Corporativo: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cham :
Springer International Publishing : Imprint: Springer,
2016.
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| Edición: | 1st ed. 2016. |
| Colección: | Advances in Experimental Medicine and Biology,
917 |
| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- Introduction
- Part I Methods of Structure Prediction
- Chapter 1 In Silico Prediction of Target-Inhibitor Interactions
- Part II Antibodies
- Chapter 2 Antibodies and Selection of Monoclonal Antibodies
- Chapter 3 Selection of Recombinant Human Antibodies
- Chapter 4 Selection of Recombinant Human Antibodies against Toxins and Viruses
- Chapter 5 Recent Advances with ER Targeted Intrabodies
- Chapter 6 Therapeutic Blocking Antibodies against Oncogenic Receptors and Growth Factors
- Chapter 7 Synthetic Cystine-Knot Miniproteins-Valuable Scaffolds for Polypeptide Engineering
- Part III Peptides, Small Molecules and Aptamers
- Chapter 8 Peptides and Peptide Analogs to Inhibit Protein
- Chapter 9 Allosteric Modulators of the Class A G Protein coupled Receptors
- Chapter 10 Phosphatases: Their Roles in Cancer and their Chemical Modulators
- Chapter 11 Selection and Application of Aptamers and Intramers
- Part IV Angiogenesis Inhibitors
- Chapter 12 Inhibitors of Angiogenesis.