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Redox-Active Therapeutics
This essential volume comprehensively discusses redox-active therapeutics, focusing particularly on their molecular design, mechanistic, pharmacological and medicinal aspects. The first section of the book describes the basic aspects of the chemistry and biology of redox-active drugs and includes a...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cham :
Springer International Publishing : Imprint: Springer,
2016.
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| Edición: | 1st ed. 2016. |
| Colección: | Oxidative Stress in Applied Basic Research and Clinical Practice,
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| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- Part 1. Pathophysiological Roles of Superoxide Dismutases (SOD)
- Superoxide and the Superoxide Dismutases: An Introduction by Irwin Fridovich
- The Discovery of Superoxide Dismutase and Its Role in Redox Biology
- Manganese Superoxide Dismutase (MnSOD) and It's Importance in Mitochondrial Function and Cancer
- Regulation of the Cellular Redox Environment by Superoxide Dismutases, Catalase and Glutathione Peroxidases During Tumor Metastasis
- Superoxide Dismutase Family of Enzymes in Brain Neurogenesis and Radioprotection
- Metabolic Production of H2O2 in Carcinogenesis and Cancer Treatment
- Part 2. Redox-Active Therapeutics - Design and Mechanisms of Action
- Mimicking SOD, Why and How: Bio-Inspired Manganese Complexes as SOD Mimics
- Mn Porphyrin-Based Redox-Active Therapeutics
- Cytochrome P450-like Biomimetic Oxidation Catalysts Based on Mn porphyrins as Redox Modulators
- Nitrones as Potent Anticancer Therapeutics
- Salen Manganese Complexes Mitigate Radiation Injury in Normal Tissues Through Modulation of Tissue Environment
- Molecular Basis for Anticancer and Antiparasite Activities of Copper-Based Drugs
- Small Signaling Molecules and CO-Releasing Molecules (CORMs) for the Modulation of the Cellular Redox Metabolism
- HNO/Thiol Biology as a Therapeutic Target
- Part 3. Redox-Active Therapeutics in Cancer
- Advances in Breast Cancer Therapy Using Nitric Oxide and Nitroxyl Donor Agents
- Mechanisms by Which Manganese Porphyrins Affect Signaling in Cancer Cells
- Targeted Therapy for Malignant Brain Tumors
- Redox Therapeutics in Breast Cancer: Role of SOD Mimics
- Anticancer Action of Mn porphyrins in Head and Neck Cancers
- Redox-based Therapeutic Strategies in the Treatment of Skin Cancers
- Role of Oxidative Stress in Erectile Dysfunction after Prostate Cancer Therapy
- Theranostic Nanoconjugates of Tetrapyrrolic Macrocycles and Their Applications in Photodynamic Therapy
- Part 4. Redox-Active Therapeutics in Other Diseases
- Quantum Dots in Photodynamic Therapy
- Metalloporphyrins in CNS injuries
- The Contribution of Nitroxidative Stress to Pathophysiological Pain and Opioid Analgesic Failure
- Amyotrophic Lateral Sclerosis - Present Understanding of the Role of SOD
- Redox Regulation and Misfolding of SOD1: Therapeutic Strategies for Amyotrophic Lateral Sclerosis
- Redox-Based Therapeutics for Prevention, Mitigation, and Treatment of Lung Injury Secondary to Radiation Exposure
- Using Metalloporphyrins to Preserve β Cell Mass and Inhibit Immune Responses in Diabetes
- Redox-Active Metal Complexes in Trypanosomatids.