Neuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems

The book presents a new, powerful model of neuronal networks, consisting of a three-dimensional neuronal culture in which 3D neuronal networks are coupled to micro-electrode-arrays (MEAs). It discusses the main advantages of the three-dimensional system compared to its two-dimensional counterpart, a...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Frega, Monica (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2016.
Edición:1st ed. 2016.
Colección:Springer Theses, Recognizing Outstanding Ph.D. Research,
Temas:
Biomedical engineering.
Cytology.
Electronics.
Neurosciences.
Biomedical Engineering and Bioengineering.
Cell Biology.
Electronics and Microelectronics, Instrumentation.
Neuroscience.
Acceso en línea:Texto Completo

MARC

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245 1 0 |a Neuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems  |h [electronic resource] /  |c by Monica Frega. 
250 |a 1st ed. 2016. 
264 1 |a Cham :  |b Springer International Publishing :  |b Imprint: Springer,  |c 2016. 
300 |a XIII, 148 p. 97 illus., 43 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
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490 1 |a Springer Theses, Recognizing Outstanding Ph.D. Research,  |x 2190-5061 
505 0 |a Introduction -- Dissociated Neuronal Networks Coupled to Micro-Electrode Arrays Devices -- In Vitro Neuronal Networks -- 3D Neuronal Networks: State of the Art -- 3D Neuronal Networks Coupled to MEAs -- Neuro-pharmacological Studies -- Discussion and Conclusion -- Data Analysis. 
520 |a The book presents a new, powerful model of neuronal networks, consisting of a three-dimensional neuronal culture in which 3D neuronal networks are coupled to micro-electrode-arrays (MEAs). It discusses the main advantages of the three-dimensional system compared to its two-dimensional counterpart, and shows that the network dynamics, recorded during both spontaneous and stimulated activity, differs between the two models, with the 3D system being better able to emulate the in vivo behaviour of neural networks. The book offers an extensive analysis of the system, from the theoretical background, to its design and applications in neuro-pharmacological studies. Moreover, it includes a concise yet comprehensive introduction to both 2D and 3D neuronal networks coupled to MEAs, and discusses the advantages, limitations and challenges of their applications as cellular and tissue-like in vitro experimental model systems. < . 
650 0 |a Biomedical engineering. 
650 0 |a Cytology. 
650 0 |a Electronics. 
650 0 |a Neurosciences. 
650 1 4 |a Biomedical Engineering and Bioengineering. 
650 2 4 |a Cell Biology. 
650 2 4 |a Electronics and Microelectronics, Instrumentation. 
650 2 4 |a Neuroscience. 
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776 0 8 |i Printed edition:  |z 9783319302362 
776 0 8 |i Printed edition:  |z 9783319302386 
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830 0 |a Springer Theses, Recognizing Outstanding Ph.D. Research,  |x 2190-5061 
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950 |a Engineering (R0) (SpringerNature-43712) 

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